Reflex Sympathetic Dystrophy

Reflex Sympathetic Dystrophy Treatment at IRIS
Complex Regional Pain Syndrome (CRPS)

Understanding Reflex Sympathetic Dystrophy: Symptoms, Diagnosis & Advanced Care

Reflex Sympathetic Dystrophy (RSD), also known as Complex Regional Pain Syndrome (CRPS), is a chronic pain condition characterized by severe, persistent pain that is disproportionate to the initial injury. It typically affects one limb and is associated with sensory, motor, and autonomic dysfunction, including swelling, temperature changes, and skin color alterations. Early diagnosis and targeted multidisciplinary treatment are crucial to managing symptoms, preventing disability, and improving quality of life. At IRIS Centre for Rheumatology, we offer world-class, patient-centric care for RSD/CRPS using the latest advances in pain management and rheumatology.

RSD/CRPS can affect anyone at any age, but it is most common in adults between 40 and 60 years. Women are affected more frequently than men. The condition can develop after trauma, surgery, stroke, or heart attack. At IRIS, our multidisciplinary team ensures comprehensive management from early diagnosis to long-term symptom control strategies.

With our state-of-the-art diagnostic approach, advanced pain management, and personalized treatment plans — including medications, nerve blocks, physical therapy, and psychological support — we aim to reduce pain, restore function, prevent progression, and enhance quality of life. Healing begins with expert care and compassion.

Reflex Sympathetic Dystrophy Symptoms

Common Symptoms of Reflex Sympathetic Dystrophy

RSD/CRPS symptoms can be divided into acute, dystrophic, and atrophic stages. Early recognition leads to better outcomes.

  • Severe, burning pain disproportionate to the injury
  • Swelling and stiffness in the affected limb
  • Changes in skin temperature (warm or cold)
  • Skin color changes (red, blue, or pale)
  • Abnormal sweating and changes in hair/nail growth
  • Muscle weakness, tremors, and limited range of motion

Diagnosis at IRIS

Early and accurate diagnosis is key to controlling RSD/CRPS. Our advanced diagnostic approach includes:

  • Comprehensive clinical examination and history of inciting event
  • Budapest Criteria for CRPS diagnosis
  • Bone scan (three-phase bone scintigraphy)
  • MRI to rule out other pathology
  • Thermography for temperature asymmetry

Advanced Treatment Options

We tailor treatments to achieve symptom control and improve life quality.

  • Pharmacotherapy: NSAIDs, Gabapentin, Pregabalin, Antidepressants
  • Sympathetic nerve blocks and epidural infusions
  • Physical and occupational therapy (mirror therapy, graded motor imagery)
  • Spinal cord stimulation for refractory cases
  • Psychological support and cognitive behavioral therapy
  • Bisphosphonates for bone-related symptoms

Why Choose IRIS for Reflex Sympathetic Dystrophy Care?

  • Expert rheumatologists with 13+ years experience
  • Advanced pain management and nerve block therapy
  • Multidisciplinary rehabilitation approach
  • Personalized medication and interventional protocols
  • Integrated physical and psychological support
  • Compassionate, patient-centric approach
  • Over 2000+ patients successfully treated
  • Ongoing support and functional restoration


IRIS Centre for Rheumatology Kollam