Henoch-Schonlein Purpura

Henoch-Schonlein Purpura Treatment at IRIS
IgA Vasculitis

Understanding Henoch-Schonlein Purpura: Symptoms, Diagnosis & Advanced Care

Henoch-Schonlein Purpura (HSP), also known as IgA Vasculitis, is an autoimmune inflammatory disorder that causes inflammation of small blood vessels, leading to a characteristic skin rash, joint pain, abdominal pain, and kidney involvement. Unlike other vasculitides, HSP is characterized by the deposition of IgA immune complexes in small vessels. Early diagnosis and targeted treatment are crucial to managing symptoms, preventing kidney damage, and improving quality of life. At IRIS Centre for Rheumatology, we offer world-class, patient-centric care for HSP using the latest advances in rheumatology.

Henoch-Schonlein Purpura is most common in children (ages 2-11 years), but it can occur in adults. Boys are affected slightly more frequently than girls. The condition often follows an upper respiratory infection. At IRIS, our multidisciplinary team ensures comprehensive management from early diagnosis to long-term remission strategies.

With our state-of-the-art immunodiagnostic laboratory, skin and kidney biopsy capabilities, and personalized treatment plans — including supportive care, corticosteroids, and immunosuppressants — we aim to halt disease progression, relieve symptoms, and prevent organ damage. Healing begins with expert care and compassion.

Henoch-Schonlein Purpura Symptoms

Common Symptoms of Henoch-Schonlein Purpura

HSP symptoms typically follow a viral illness. Early recognition leads to better outcomes.

  • Palpable purpura (raised red-purple rash on legs and buttocks)
  • Joint pain and swelling (arthritis/arthralgia)
  • Abdominal pain, nausea, vomiting (gastrointestinal)
  • Bloody stools (gastrointestinal bleeding)
  • Kidney involvement (hematuria, proteinuria)
  • Scrotal swelling (in males)

Diagnosis at IRIS

Early and accurate diagnosis is key to controlling HSP. Our advanced diagnostic tools include:

  • Comprehensive clinical examination & rash assessment
  • Blood tests: ESR, CRP, IgA levels
  • Urinalysis for kidney involvement
  • Skin biopsy (leukocytoclastic vasculitis with IgA deposition)
  • Kidney biopsy for severe renal disease

Advanced Treatment Options

We tailor treatments to achieve remission and improve life quality.

  • Supportive care (rest, hydration) for mild cases
  • NSAIDs for joint pain (avoid in kidney disease)
  • Corticosteroids for abdominal pain or kidney involvement
  • Immunosuppressive agents for severe renal disease
  • ACE inhibitors for persistent proteinuria
  • Regular monitoring of blood pressure and kidney function

Why Choose IRIS for Henoch-Schonlein Purpura Care?

  • Expert rheumatologists with 13+ years experience
  • ISO 9001:2015 Certified & NABH accredited lab
  • On-site skin and kidney biopsy capabilities
  • Personalized immunosuppressive therapy monitoring
  • Integrated nephrology and gastroenterology care
  • Compassionate, patient-centric approach
  • Over 2000+ patients successfully treated
  • Long-term follow-up for kidney function


IRIS Centre for Rheumatology Kollam