Polymyositis

Inflammatory Myositis without Skin Involvement

Understanding Polymyositis: Symptoms, Diagnosis & Advanced Care

Polymyositis is a rare autoimmune inflammatory disorder that primarily affects the muscles, causing progressive symmetrical muscle weakness. Unlike dermatomyositis, polymyositis occurs without skin manifestations, when the immune system directly attacks muscle fibers. Early diagnosis and targeted treatment are crucial to managing symptoms, preventing muscle damage, and improving quality of life. At IRIS Centre for Rheumatology, we offer world-class, patient-centric care for polymyositis using the latest advances in rheumatology.

Polymyositis can affect anyone at any age, but it most commonly occurs in adults between 30 and 60 years. Women are affected more frequently than men. The condition may also cause systemic inflammation affecting the lungs, heart, and blood vessels, and is associated with an increased risk of malignancy. At IRIS, our multidisciplinary team ensures comprehensive management from early diagnosis to long-term remission strategies.

With our state-of-the-art immunodiagnostic laboratory, electromyography, and personalized treatment plans — including immunosuppressants, biologics, and physiotherapy — we aim to halt disease progression, relieve symptoms, and restore muscle strength. Healing begins with expert care and compassion.

Common Symptoms of Polymyositis

Polymyositis symptoms typically develop gradually. Early recognition leads to better outcomes.

• Progressive proximal muscle weakness (shoulders, hips)
• Difficulty rising from seated position or climbing stairs
• Difficulty lifting arms or swallowing (dysphagia)
• Muscle pain and tenderness
• Fatigue, fever, and weight loss
• Shortness of breath (interstitial lung disease)